Science and clinic

Publications

Studies on CARDIOLAB, REOCOM, NEUROCOM and SPIROCOM systems.

Scientific papers and an ECG strip

The diagnostic systems are backed by clinical studies, dissertations and 30 years of use.

  • Vegetology HRV analysis for adaptation assessment.
  • Hemodynamics Endothelial function and vascular tone.
  • Neurophysiology EEG patterns and neurodynamics.
  • Pulmonology COPD monitoring and respiratory function.

Some links go to external repositories; full text depends on the publisher. Without a translation, the paper stays in the original language.

CardioLab - Electrocardiography and HRV

Equipment

Scientific Study: Effect of caffeine on heart rate variability in doxorubicin cardiomyopathy

Experimental study, 2025. In press. Analysis via CardioLab.

Hypodynamia and gonadectomy: impact on HRV parameters in experimental rats

Experimental Physiology Group, 2025. Pre-print. Research on adaptive capabilities.

Nazarenko V. I., Berestovskyi O. S., Moroz H. Z. Heart rate variability in COVID-19 patients with different levels of cardiovascular risk

Wiadomości Lekarskie, 2022, Vol. 75, Iss. 4, pp. 845-850. HRV study in COVID-19.

Kudiy L. I., Varetska O. V., Kudiy S. V. Reliability of "Rytm" software for heart rate variability analysis

Journal of Physical Education and Sport, 2020, Vol. 20 (6), Art 427, pp. 3154-3160. "Rytm" SW validation.

Source

Davidich Yu., Kush Ye., Ponkratov D. Changes in the driver’s stress index during different periods of the day in urban traffic

Transport Technologies, 2020, Iss. 1, No. 2. Measurements with KHAI-MEDICA equipment.

Source

Kentesh O. P., Nemesh M. I. Functional state of the autonomic nervous system depending on the body composition

Wiadomości Lekarskie, 2018, Vol. 71, Iss. 2, pp. 312-316.

Tymoshchuk O. V. Diagnosis of adaptation disorders in children with chronic gastroduodenitis based on HRV indicators

Child's Health, 2016, No. 7 (75). Autonomic status assessment.

Syvolap V. D., Kyselov S. M. Level of matrix metalloproteinase-9 and myocardium remodeling in patients with acute postinfarction aneurism of left ventricle

Zaporozhye Medical Journal.

Source

Syvolap V. V., Kyselov S. M., Apolikhin O. I. Structural-geometric and functional assessment of myocardium in patients with stage II hypertension

Zaporozhye Medical Journal, 2012, No. 1 (70), pp. 34-37. CardioLab application.

Yavorskyy B. I., Zabytivskyy V. P. Identification of morphological parameters of a computational model of the electrocardiosignal

Bulletin of TSTU, 2008, Vol. 13, No. 3, pp. 115–120. Mentions KHAI-MEDICA equipment.

Source

ReoCom - Rheography and Endothelial Function

Equipment

Patent No. 121689: Method for assessing central aortic pressure

Registered in the State Patent Register of Ukraine, 10.07.2020.

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Patent No. 120800: Method for measuring blood pressure

Registered in the State Patent Register of Ukraine, 10.02.2020.

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Patent No. 118939: Method for assessing the function of arterial vessel endothelium

Registered in the State Patent Register of Ukraine, 25.03.2019.

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Study of endothelial regulation of vascular tone (Parts 1 and 2)

Methodological guide, 2014. XAI-Medica. Step-by-step guide.

Part 1Part 2

Fedorov A. A. Functional state of endothelium in patients with vasospastic angina

Journal of Cardiovascular Diseases, 2014. Clinical study.

Penelova Z. V. Features of psychophysiological reaction when using the "ReoCom-stress" complex

Zaporozhye Medical Journal, 2013, No. 4 (79).

Blood pressure in symmetric vascular basins: rheographic assessment

Methodological article, 2012. Measurement protocol with ReoCom.

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Assessment of cerebral blood flow volumetric velocity (according to Paleev)

XAI-Medica Methodological guide, 2008. Kharkiv.

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Selection of informational parameters in rheographic assessment of endothelial function in a reactive hyperemia test

XAI-Medica Methodological Recommendations, 2007. Kharkiv.

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Assessment of the vascular system based on rheographic measurement results

Scientific and methodological review. Data interpretation algorithms.

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New approaches to vascular system assessment based on rheographic studies

Methodological materials. Application in clinical practice.

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Pulse wave velocity and elastic properties of arterial vessels

Methodological development. Arterial stiffness assessment.

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Rheographic assessment of peripheral circulation (Full archive)

XAI-Medica Collection. Methods and results.

PDF

NeuroCom - Electroencephalography

Equipment

Bryk O., Pastukh O. Extraction of important data for cognitive software systems based on data science

Scientific Journal of TNTU, 2025, Vol. 117, No. 1, pp. 62–66. EEG via NeuroCom.

Source

Stefanyshyn V., Stefanyshyn I., Pastukh O., Kulikov S. Comparison of the accuracy of machine learning algorithms for brain-computer interaction based on high-performance computing technologies

Scientific Journal of TNTU, 2024, Vol. 115, No. 3, pp. 82–90. KHAI-MEDICA equipment.

Source

Pastukh O., Yatsyshyn V. Development of software for neuromarketing based on artificial intelligence and data science using high-performance computing and parallel programming technologies

Scientific Journal of TNTU, 2024, Vol. 113, No. 1, pp. 143–149. EEG research.

Source

Mushta S. A., Palamar S. P., Harmatiuk D. V., Popov A. O., Alves Ferreira J. M., Makarchuk M. Yu., Tukaiev S. V. EEG frequencies pattern as brain signature of emotional burnout. Anxiety tension stage formation

Clinical and Preventive Medicine, 2025, No. 1 (39), pp. 92–100.

Source

Yukhymenko O. V. Features of EEG patterns in individuals with different functional mobility of nervous processes

PhD Thesis. Taras Shevchenko National University of Kyiv, 2015. NeuroCom research.

Shpenkov O. O., Tukaiev S. V., Zyma I. G., Kryzhanovskyi S. A. EEG dynamics during listening to rock music with modified frequency structure

Cherkasy University Bulletin: Biological Sciences Series, 2016.

Source

Kryzhanovsky S. A. Correlation between activity efficiency and EEG parameters

Neurophysiology, 2009. Fundamental study.

SpiroCom - Spirometry

Equipment

Tyshchenko V., Bosenko A., Kozak Ye., Denysovets A., Atamanyuk S., Veritov O., Ruda I. Enhancing respiratory function through Yoga and Pilates in women aged 45-50

Pedagogy of Physical Culture and Sports, 2024, 28(5), pp. 449–455.

Source

Feshchenko Yu. I. Monitoring of respiratory function in patients with COPD using digital complexes

Asthma and Allergy, 2020, No. 3. Clinical efficiency.

Combined Studies

Kentesh O. P. Impact of autonomic dysfunction on the state and function of the endothelium in young individuals (CardioLab + ReoCom)

PhD Thesis. Uzhhorod National University, 2018.

PDF

Spirina I. D. Psychophysiological aspects of adaptation and the functional state of the vascular system

Journal of Psychiatry and Psychopharmacotherapy, 2013. Comprehensive diagnostics.

Research collaboration: research@xai-medica.com

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